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Sequence No.

BIO-853

What is the difference between pro - insulin and mature insulin?
Or
How pro - insulin undergoes for maturation?
Or
Why is proinsulin so called? How is proinsulin different from functional insulin in humans?

 

Answer:

Pro - insulin is naturally synthesised by human and other mammals contain a c - peptide chain that does not found in mature insulin. Pro - insulin contain three chains A, B and C, when pro - insulin undergoes maturation c - peptide separate out from insulin and fully mature insulin only contain two A and B chains, bonded with di - sulfide bond.

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BIO-853

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